Minister of State for External Affairs Shashi Tharoor has been India's answer to Ashton Kutcher in the role that he has played in popularising the microblogging service, Twitter. But many people get frustrated with the service after using Twitter, which, despite some improvements, is not that great.
This is why power-users of Twitter use third-party software to manage their accounts, and for the PC, the most popular and probably the best piece of software is TweetDeck. Though you will need to install Adobe's AIR platform to run TweetDeck, this software is great in that it allows you to maintain and update multiple Twitter accounts. The software automatically shortens web links and makes it pretty easy to upload pictures.
On other devices, there are some great apps as well, such as TwitterBerry and UberTwitter for BlackBerry users or EchoFon and Twitterific for iPhone users. While these are all free, Gravity for Nokia S60 devices is a paid software.