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COVID-19 vaccination: Covaxin's efficacy data likely to bolster public acceptance

Government data shows that only 10% of about 12.6 million people immunised in India have taken the COVAXIN shot, which was found to be 81% effective in an interim analysis of the late-stage trial, its developer Bharat Biotech said

twitter-logoReuters | March 4, 2021 | Updated 11:19 IST
COVID-19 vaccination: Covaxin's efficacy data likely to bolster public acceptance
Many Indian doctors and opposition politicians had rejected COVAXIN because it was approved by the drug regulator only on the basis of data from intermediate trials

Indian doctors and politicians on Thursday welcomed efficacy data for a state-backed coronavirus vaccine that was given emergency approval in January without the completion of a late-stage trial, making people reluctant to receive the shot. Government data shows that only 10% of about 12.6 million people immunised in India have taken the COVAXIN shot, which was found to be 81% effective in an interim analysis of the late-stage trial, its developer Bharat Biotech said on Wednesday.

Any boost to the vaccine's acceptance in India, which on Thursday reported a new COVID-19 cases at their highest in five weeks, could also brighten its export prospects. Bharat Biotech said 40 countries were interested in COVAXIN.

Many Indian doctors and opposition politicians had rejected COVAXIN because it was approved by the drug regulator only on the basis of data from intermediate trials. The regulator has also authorised the use of the Oxford University/AstraZeneca vaccine, marketed as Covishield in India, which was found to be 70.42% effective based on overseas trials.

"Now that interim Phase 3 data are available for COVAXIN, I can safely ask my father, who is more than 60 years of age and a diabetic, to get it," said Nirmalya Mohapatra, a leader of an association of doctors at New Delhi's Ram Manohar Lohia Hospital, having previously publicly refused to take COVAXIN.

Rajib Dasgupta, chairperson of the Centre of Social Medicine & Community Health at New Delhi's Jawaharlal Nehru University, said the interim results were encouraging but that a "well-rounded picture" would emerge only after a fuller analysis. Opposition lawmaker Shashi Tharoor welcomed Bharat Biotech's announcement. "For those like me who were concerned that COVAXIN was being deployed before its third phase trials were concluded, this is good news indeed," he said on Twitter.

India reported 17,407 COVID-19 cases in the past 24 hours, taking the total to 11.16 million. Deaths rose by 89 to 157,435.

Also read: Covaxin exceeds efficacy of most traditional platform-based COVID-19 vaccines

Also read: Bharat Biotech's Covaxin 81% effective, works against UK variant

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