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Syngene targets supplying 500,000 Remdesivir vials in India amid COVID-19 surge

Syngene, majority owned by biopharmaceutical company Biocon Ltd, is one of the seven Indian companies that have licensed remdesivir from U.S.-based Gilead Sciences Inc

India's Syngene International Ltd aims to supply half-a-million vials of COVID-19 drug remdesivir through its local distribution partners next month, its top executive said, as the country faces shortages of the medicine amid a second wave. "At the moment we are operating at near maximum capacity (to produce remdesivir)," Chief Executive Officer Jonathan Hunt told Reuters on Wednesday.

"I'd expect the volume of drug that we are supplying into the Indian market to step up as we get into May," he added. Hunt did not provide details on how many vials the company has already delivered.

Syngene, majority owned by biopharmaceutical company Biocon Ltd, is one of the seven Indian companies that have licensed remdesivir from U.S.-based Gilead Sciences Inc. The seven companies together have a total installed capacity of about 3.9 million units per month.

"Across all seven manufacturers, (Syngene is) probably one of the smallest by capacity, but you are seeing everybody working round the clock...to boost the supply," Hunt said. This follows Gilead's announcement on Monday that it would donate a minimum of 450,000 vials of the drug to the Indian government.

The country's death toll from the pandemic crossed the 200,000 mark on Wednesday, worsened by shortages of hospital beds and medical oxygen.

Remdesivir is approved in India for restricted emergency use to treat severe COVID-19 cases, despite the World Health Organisation advising against using the drug due to doubts about its effectiveness in treating the infection. Indian health officials have said it is only to be used in a hospital setting for patients who need oxygen.

Syngene, headquartered in the southern technology hub of Bengaluru, offers contract research and manufacturing to global drugmakers. Its clients include U.S. pharma majors Amgen Inc and Bristol-Myers Squibb Co. The company late on Tuesday reported a 33.6% jump in consolidated profit to 1.61 billion rupees ($21.63 million) for the fourth-quarter ended March 31.

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